Professor Zhou Guohua of Nanjing University develops a new generation of gene editing technology

On September 15th, Genome Biology (IF: 11.313), a leading genomics journal, published a breakthrough achievement in the new gene editing technology from Nanjing University. The authors of this article are Professor Zhou Guohua of Jinling Hospital affiliated to Nanjing University Medical College, Professor Zhao Qingshun and Professor Zhu Minsheng of Nanjing University Model Animal Institute. In the same period, "Genome Biology" distributed a commentary article "DNA-guided genome editing using structure-guided endonucleases". In recent years, the development of gene editing has been leaping forward, especially in May this year, Hebei University of Science and Technology Han Chunyu's controversy on NgAgo reported in Nature Biotechnology turned out to be the birth of many domestic ordinary bosses. It is. Today BioArt no longer discusses the repetitiveness of NgAgo, let us turn our attention to the breakthrough results published by Nanjing University recently. BioArt has the honor to invite the practitioners of gene editing technology, Mr. Yi Hong and Dr. Jiang Wei, to write a critical article entitled “From Natural, Beyond Nature – Professor Zhou Guohua from Nanjing University, Reading the DNA Editing Paper”.

Professor Zhou Guohua of Nanjing University develops a new generation of gene editing technology

Professor Zhou Guohua of Nanjing University develops a new generation of gene editing technology

Professor Zhou Guohua of Nanjing University develops a new generation of gene editing technology

On September 15, 2016, "Genome Biology" reported a new SGN-based gene editing technology that uses the structure-guided endonuclease (SGN) to target and cleave arbitrary sequences of DNA in vitro and in vivo. In the first paper, Shu Xu, the author of the paper is Guohua Zhou, a researcher at Jinling Hospital affiliated to Nanjing University Medical College, and Professor Qingshun Zhao and Minsheng Zhu at the Institute of Model Animals, Nanjing University. As a practitioner in the field of genetic editing, I feel very touched after reading. At the invitation of BioArt editor, I will write it in a semi-academic way and in the form of an essay. I will share it with you. If you are not rigorous, please disinfect each other.

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