Nature: Parkinson's disease or an autoimmune disease

By "qualifying" a disease, scientists can develop targeted treatments, or learn from each other in the same kind of disease, and get some treatment ideas. Otherwise, the development of the therapy will take many detours. And the latest study suggests that perhaps we have made a mistake in the qualitative nature of a famous disease, Parkinson's disease!

As you may know, Parkinson's disease has long been considered a neurodegenerative disease. The reason for this is that, on the surface, it is in line with the definition of neurodegenerative diseases. A protein called α-synuclein (α-Syn) in dopamine neurons is misfolded and accumulated, and cannot be Degradation, the state of the disease caused by the death of neurons, the body will have some dysfunction, and it will deteriorate over time.

《自然》:帕金森病或是一种自身免疫性疾病

But in a new study published in Nature, researchers from Columbia University Medical Center and the La Jolla Institute of Allergy and Immunity believe that Parkinson's disease should be an autoimmune disease!

Why do you say that? First we need to understand what is an autoimmune disease. An autoimmune disease is a disease caused by the body's immune response to its own antigen, which causes damage to its own tissues. Here is a key singularity cake to draw: antigen.

《自然》:帕金森病或是一种自身免疫性疾病

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